DNA diagnostics for a predisposition to type 2 diabetes
What is diabetes?
Diabetes is a dangerous disease. It is widespread in developed countries and leads to disability and mortality. Type 2 diabetes is a metabolic multifactorial disease with a hereditary predisposition characterized by impaired insulin secretion or mechanisms of its interaction with tissue cells. Type 2 diabetes accounts for 85-90% of all diabetes forms and most often develops in people over 40 years of age, especially those consuming the large amounts of carbohydrates.
How are genetics and diabetes risk related?
The key role in the disease pathogenesis is played by metabolic disorders associated with polymorphisms in the genes TCF7L2, PPARG, KCNJ11 and UCP2, which affect the insulin level in blood, lipoprotein metabolism, the development of metabolic syndrome, the division and differentiation of adipocytes and, in certain variants, increase or decrease the risk of disease development. The detection of risk variants indicates an increased probability of type 2 diabetes. The risk level is associated with age, increased body weight, physical inactivity, the increased consumption of easily digestible carbohydrates etc.
Who is genetic testing recommended for?
The identification of a predisposition to type 2 diabetes is recommended for people with increased glucose levels in blood (usually determined on an empty stomach), in the presence of diseases that together form metabolic syndrome (hypertension, ischemia and obesity); for people leading a sedentary lifestyle, excessively consuming easily digestible carbohydrates, and if there are relatives with type 2 diabetes.
How will it help?
The early identification of a genetic predisposition to type 2 diabetes allows the prevention of this disease.
Genetic testing fees
- Testing of 8 genes predisposing to diabetes
- Professor’s conclusion
FAQs
Is special preparation required before providing test material?
No, it is not necessary. There is no need to follow a diet or perform any other special actions before providing material for testing. Taking medications, alcohol etc. will not affect genetic testing results either.
How soon will test results be ready?
Up to 35 working days from the date of signing an agreement. In fact, much sooner: 2-3 weeks.
What do I need to have with me to submit material for testing?
You should have your passport and money on you. Minors must be accompanied by an adult.
What are your working hours?
Our working hours for clients with a booked appointment and providing test results.
On working days: Monday ‒ Thursday, from 9:00 till 17:30; on Fridays: from 9:00 till 16:30.
Days off: Saturday & Sunday.
What biological material is collected for testing and how?
For testing, buccal epithelium (epithelium of the inner part of your cheeks) is collected with a special cotton swab. It is done by a client himself or herself in the presence of a laboratory diagnostics doctor. Blood is not collected.
Can I send biological material for testing by post?
Yes, it is possible. Please follow the link for detailed instructions. The test results can be received in hard copy by mail to your home directly. Where DNA cannot be isolated from the sample provided, you will need to reimburse the cost of the reagents used.
Accreditation
The Certificate of Conformity to STB ISO 9001-2015 No. BY/112 05.01. 077.01 00132 valid till December 3, 2026
License
License of the Ministry of Health of the Republic of Belarus for the right to provide medical services of June 17, 2011, No. 02040/6875
Certificate
Certificate of the Reference Institute for Bioanalytics, Bonn, Germany (Referenzinstitut für Bioanalytik, Bonn, Deutschland) issued on April 3, 2021