COMT (32519G>A) (catechol-O-methyltransferase gene )

The gene is present in the following complexes:

DNA diagnostics of a person’s psycho-emotional status

The major genotype A/A is more common in the group of individuals with decreased phenotypic psycho-emotional stability, which may be due to the fact that rs165599 is linked to rs4680. The genotype A/A and the allele A are unfavorable in terms of the formation of a tendency to anxiety and are associated with the risk of bipolar depression development. A/G is an intermediate genotype; G/G is characterized by psycho-emotional stability.