DNA diagnostics of caffeine metabolism efficiency
Different variants of the cytochrome CYP1A2 enzyme, determined by the CYP1A2 gene polymorphism (variation), have different activity, and caffeine is metabolized at a higher or lower rate. In people with low CYP1A2 enzyme activity, i.e. slow metabolism, caffeine has a stronger and longer effect, which increases the likelihood of side effects. In people with high CYP1A2 enzyme activity, the effect of caffeine is short, which allows consuming more caffeine-containing drinks/products without any harm to your health. Do you have a fast caffeine metabolism? Consuming up to 300 mg of caffeine per day has a beneficial effect on the cardiovascular system.