DRD2 (C/T rs1800497) (dopamine receptor D2 gene)

The gene is present in the following complexes:

DNA diagnostics of a person’s psycho-emotional status

The minor genotype T/T carriers are characterized by decreased phenotypic emotional stability; they are characterized by a higher level of perceived stress. The carriers of C/C and C/T variants have a normal level of stress resistance. The T allele carriers have a decrease in the density of dopamine receptors by 30-40% in the striatum, which leads to decreased attention and learning ability and increased anxiety; an association with the reward deficiency syndrome and novelty seeking is observed.