AGTR1 (А1166С) (angiotensin II type 1 receptor gene)

The gene is present in the following complexes:

DNA diagnostics for a predisposition to pregnancy loss

The substitution of adenine (A) for cytosine (C) affects the functional activity of the angiotensin II type 1 receptor. Such changes may cause alterations in the proliferation of elements through the vascular wall, affect the regulation of vessel lumen and lead to their obstruction, which will cause pregnancy pathology.