ITGA2 (C807T) (integrin subunit alpha 2)

The gene is present in the following complexes:

DNA diagnostics for a predisposition to pregnancy loss

The ITGA2 gene encodes alpha-2-membrane glycoprotein; ensures the interaction of platelets with the damaged vascular wall, which is a required condition for the inclusion of subsequent chains of the blood coagulation system. The allelic variant T/T is associated with an increased rate of platelet adhesion, which may be a thrombophilia risk factor.

DNA diagnostics for a predisposition to thrombosis and hypertensive crises

The ITGA2 gene encodes the alpha-2-membrane glycoprotein protein; ensures the interaction of platelets with the damaged vascular wall, which is a necessary condition for the inclusion of subsequent links in the blood coagulation system. The presence of the T allele is associated with an increase in the rate of platelet adhesion, which may be a risk factor for thrombophilia.