ITGB3 (T1565C) (integrin beta 3 binding protein)

The gene is present in the following complexes:

DNA diagnostics for a predisposition to pregnancy loss

It is responsible for the interaction of platelets on the surface of which it is located with blood plasma fibrinogen, which leads to platelet aggregation and thrombus formation. The presence of the C allele of ITGB3 T1565C is associated with an increased frequency of habitual miscarriage – the risk of reproductive loss increases by 3.6 times.