LDLR (7TA,8TA,10TA,11TA) (low density lipoprotein receptor)

The gene is present in the following complexes:

DNA diagnostics for a predisposition to hypercholesterolemia

It regulates the concentration of cholesterol from blood plasma. Low-density lipoprotein is the main representative of the class of plasma lipoproteins that carry cholesterol; its excess is one of the main risk factors of atherosclerosis. Alleles 8TA and 11TA — myocardial infarction risk.