The FGG gene encodes fibrinogen gamma chain, which is one of three peptides that form fibrinogen subunits. An association of the allelic variant TT of the FGG fibrinogen gene with the risk of venous thrombosis development, including in women during pregnancy, has been shown. Fibrinogen deficiency can lead to chorionic/placental abruption.
The FGG gene encodes fibrinogen gamma chain, which is one of three peptides forming fibrinogen subunits. Mutations in the FGG gene result in the impaired gamma chain synthesis, which is characterized by a complete absence of fibrinogen or its partial decrease in blood and leads to impaired blood clotting. The T allele is associated with the risk of venous thrombosis development.
The FGG gene encodes fibrinogen gamma chain, which is one of three peptides forming fibrinogen subunits. Mutations in the FGG gene result in the impaired gamma chain synthesis, which is characterized by a complete absence of fibrinogen or its partial decrease in blood and leads to impaired blood clotting. The T allele is associated with the risk of venous thrombosis development.