UCP2 (Ala55Val) (uncoupling protein)

The gene is present in the following complexes:

DNA diagnostics for a predisposition to type 2 diabetes

The Val allele is associated with the high metabolic efficiency of muscle and physical activity with reduced energy expenditure at rest, the low utilization of fatty acids and the risk of type 2 diabetes mellitus and obesity. The Val/Val homozygote carriers must be highly physically active throughout their lives; otherwise there is a risk of metabolic disorders’ development.

DNA diagnostics for a predisposition to metabolic syndrome

The Val allele is associated with the high metabolic efficiency of muscle and physical activity, reduced energy expenditure at rest and the low utilization of fatty acids. The Val/Val homozygote carriers must be highly physically active throughout their lives; otherwise there is a risk of metabolic disorders’ development.

DNA diagnostics for a predisposition to high sporting achievements

The Val allele is associated with the high metabolic efficiency of muscle and physical activity, reduced energy expenditure at rest, the low utilization of fatty acids and the risk of type 2 diabetes and obesity development. The Val/Val homozygote carriers must be highly physically active throughout their lives; otherwise there is a risk of metabolic disorders’ development. The Val allele is associated with endurance; and Ala is the allele of speed and strength.